{"id":3353,"date":"2022-07-19T09:00:16","date_gmt":"2022-07-19T00:00:16","guid":{"rendered":"https:\/\/qard.is.tohoku.ac.jp\/T-Wave\/?p=3353"},"modified":"2022-07-19T09:00:16","modified_gmt":"2022-07-19T00:00:16","slug":"%e6%a9%9f%e6%a2%b0%e5%ad%a6%e7%bf%92%e3%81%a7%e3%82%ac%e3%83%b3%e3%82%92%e5%88%86%e9%a1%9e%e3%81%99%e3%82%8b","status":"publish","type":"post","link":"https:\/\/qard.is.tohoku.ac.jp\/T-Wave\/2022\/07\/19\/%e6%a9%9f%e6%a2%b0%e5%ad%a6%e7%bf%92%e3%81%a7%e3%82%ac%e3%83%b3%e3%82%92%e5%88%86%e9%a1%9e%e3%81%99%e3%82%8b\/","title":{"rendered":"\u91cf\u5b50\u30a2\u30cb\u30fc\u30ea\u30f3\u30b0\u306f\u30ac\u30f3\u7d30\u80de\u306e\u8b58\u5225\u306b\u9069\u3057\u3066\u3044\u308b\uff1f"},"content":{"rendered":"\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-white ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title ez-toc-toggle\" style=\"cursor:pointer\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/qard.is.tohoku.ac.jp\/T-Wave\/2022\/07\/19\/%e6%a9%9f%e6%a2%b0%e5%ad%a6%e7%bf%92%e3%81%a7%e3%82%ac%e3%83%b3%e3%82%92%e5%88%86%e9%a1%9e%e3%81%99%e3%82%8b\/#%E6%96%87%E7%8C%AE%E6%83%85%E5%A0%B1\" >\u6587\u732e\u60c5\u5831<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/qard.is.tohoku.ac.jp\/T-Wave\/2022\/07\/19\/%e6%a9%9f%e6%a2%b0%e5%ad%a6%e7%bf%92%e3%81%a7%e3%82%ac%e3%83%b3%e3%82%92%e5%88%86%e9%a1%9e%e3%81%99%e3%82%8b\/#%E6%A6%82%E8%A6%81\" >\u6982\u8981<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/qard.is.tohoku.ac.jp\/T-Wave\/2022\/07\/19\/%e6%a9%9f%e6%a2%b0%e5%ad%a6%e7%bf%92%e3%81%a7%e3%82%ac%e3%83%b3%e3%82%92%e5%88%86%e9%a1%9e%e3%81%99%e3%82%8b\/#%E6%96%B9%E6%B3%95\" >\u65b9\u6cd5<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/qard.is.tohoku.ac.jp\/T-Wave\/2022\/07\/19\/%e6%a9%9f%e6%a2%b0%e5%ad%a6%e7%bf%92%e3%81%a7%e3%82%ac%e3%83%b3%e3%82%92%e5%88%86%e9%a1%9e%e3%81%99%e3%82%8b\/#%E7%B5%90%E6%9E%9C1%EF%BD%9C%E3%82%AC%E3%83%B3%E7%A8%AE%E9%A1%9E%E5%88%A5%E3%81%AE%E5%88%86%E9%A1%9E%E6%80%A7%E8%83%BD\" >\u7d50\u679c1\uff5c\u30ac\u30f3\u7a2e\u985e\u5225\u306e\u5206\u985e\u6027\u80fd<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/qard.is.tohoku.ac.jp\/T-Wave\/2022\/07\/19\/%e6%a9%9f%e6%a2%b0%e5%ad%a6%e7%bf%92%e3%81%a7%e3%82%ac%e3%83%b3%e3%82%92%e5%88%86%e9%a1%9e%e3%81%99%e3%82%8b\/#%E7%B5%90%E6%9E%9C2%EF%BD%9C%E5%AD%A6%E7%BF%92%E3%83%87%E3%83%BC%E3%82%BF%E6%95%B0%E3%81%AE%E4%BE%9D%E5%AD%98%E6%80%A7\" >\u7d50\u679c2\uff5c\u5b66\u7fd2\u30c7\u30fc\u30bf\u6570\u306e\u4f9d\u5b58\u6027<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/qard.is.tohoku.ac.jp\/T-Wave\/2022\/07\/19\/%e6%a9%9f%e6%a2%b0%e5%ad%a6%e7%bf%92%e3%81%a7%e3%82%ac%e3%83%b3%e3%82%92%e5%88%86%e9%a1%9e%e3%81%99%e3%82%8b\/#%E7%B5%90%E8%AB%96\" >\u7d50\u8ad6<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/qard.is.tohoku.ac.jp\/T-Wave\/2022\/07\/19\/%e6%a9%9f%e6%a2%b0%e5%ad%a6%e7%bf%92%e3%81%a7%e3%82%ac%e3%83%b3%e3%82%92%e5%88%86%e9%a1%9e%e3%81%99%e3%82%8b\/#%E3%81%82%E3%81%A8%E3%81%8C%E3%81%8D\" >\u3042\u3068\u304c\u304d<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/qard.is.tohoku.ac.jp\/T-Wave\/2022\/07\/19\/%e6%a9%9f%e6%a2%b0%e5%ad%a6%e7%bf%92%e3%81%a7%e3%82%ac%e3%83%b3%e3%82%92%e5%88%86%e9%a1%9e%e3%81%99%e3%82%8b\/#%E6%9C%AC%E8%A8%98%E4%BA%8B%E3%81%AE%E6%8B%85%E5%BD%93%E8%80%85\" >\u672c\u8a18\u4e8b\u306e\u62c5\u5f53\u8005<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/qard.is.tohoku.ac.jp\/T-Wave\/2022\/07\/19\/%e6%a9%9f%e6%a2%b0%e5%ad%a6%e7%bf%92%e3%81%a7%e3%82%ac%e3%83%b3%e3%82%92%e5%88%86%e9%a1%9e%e3%81%99%e3%82%8b\/#%E8%A3%9C%E8%B6%B3%EF%BD%9C%E8%A9%95%E4%BE%A1%E6%8C%87%E6%A8%99%E3%81%AB%E3%81%A4%E3%81%84%E3%81%A6\" >\u88dc\u8db3\uff5c\u8a55\u4fa1\u6307\u6a19\u306b\u3064\u3044\u3066<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%96%87%E7%8C%AE%E6%83%85%E5%A0%B1\"><\/span>\u6587\u732e\u60c5\u5831<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>\u30bf\u30a4\u30c8\u30eb\uff1aQuantum-processor inspired machine learning in the biomedical sciences<\/li><li>\u8457\u8005\uff1aRichard Y. Li, Sharvari Gujja, Sweta R. Bajaj, Omar E. Gamel, Nicholas Cilfone, Jeffrey R. Gulcher, Daniel A. Lidar, Thomas W. Chittenden<\/li><li>\u66f8\u8a8c\u60c5\u5831\uff1a<i>Patterns<\/i> <strong>2<\/strong>(6), 2021, <a href=\"https:\/\/doi.org\/10.1016\/j.patter.2021.100246\">10.1016\/j.patter.2021.100246<\/a><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%A6%82%E8%A6%81\"><\/span>\u6982\u8981<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u8fd1\u5e74\u3001\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u306e\u9ad8\u6027\u80fd\u306a\u51e6\u7406\u80fd\u529b\u3092\u5229\u7528\u3057\u305f\u9ad8\u5ea6\u306a\u30b2\u30ce\u30e0\u89e3\u6790\u6280\u8853\u306b\u3088\u3063\u3066\u3001\u8907\u96d1\u306a\u5206\u5b50\u30ec\u30d9\u30eb\u3067\u30d2\u30c8\u75be\u60a3\u306e\u539f\u56e0\u3092\u89e3\u660e\u3059\u308b\u53d6\u308a\u7d44\u307f\u304c\u306a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u4e00\u65b9\u3067\u3001\u5f93\u6765\u578b\u306e\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u3084\u305d\u308c\u3092\u5229\u7528\u3057\u305f\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306e\u6027\u80fd\u306e\u982d\u6253\u3061\u304c\u8fd1\u3065\u3044\u3066\u3044\u308b\u3053\u3068\u3082\u4e8b\u5b9f\u3067\u3059\u3002\u305d\u3053\u3067\u3001\u672c\u8ad6\u6587\u3067\u306f\u8fd1\u5e74\u9032\u6b69\u3092\u7d9a\u3051\u308b\u91cf\u5b50\u30a2\u30cb\u30fc\u30ea\u30f3\u30b0\u6280\u8853\u3092\u7528\u3044\u3066\u30ac\u30f3\u30c7\u30fc\u30bf\u306e\u5206\u985e\u3092\u884c\u3044\u3001\u65e2\u5b58\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u3068\u306e\u6bd4\u8f03\u8a55\u4fa1\u3092\u884c\u3044\u307e\u3059\u3002\u91cf\u5b50\u30a2\u30cb\u30fc\u30ea\u30f3\u30b0\u306f\u3001\u91cf\u5b50\u52b9\u679c\u3092\u7528\u3044\u3066\u30a4\u30b8\u30f3\u30b0\u6a21\u578b\u306e\u57fa\u5e95\u72b6\u614b\u3092\u63a2\u7d22\u3057\u307e\u3059\u3002\u3053\u306e\u30a4\u30b8\u30f3\u30b0\u6a21\u578b\u306e\u57fa\u5e95\u72b6\u614b\u3092\u53e4\u5178\u7684\u306a\u8a08\u7b97\u306b\u3088\u3063\u3066\u63a2\u7d22\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306a\u30b7\u30df\u30e5\u30ec\u30fc\u30c6\u30c3\u30c9\u30a2\u30cb\u30fc\u30ea\u30f3\u30b0\u306e\u6027\u80fd\u3082\u8a55\u4fa1\u3057\u307e\u3059\u3002\u305d\u306e\u7d50\u679c\u3001\u30a4\u30b8\u30f3\u30b0\u6a21\u578b\u3092\u7528\u3044\u305f\u6a5f\u68b0\u5b66\u7fd2\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306f\u3001\u5b66\u7fd2\u30c7\u30fc\u30bf\u304c\u5c11\u306a\u3044\u5834\u5408\u306b\u512a\u308c\u305f\u5206\u985e\u6027\u80fd\u3092\u6301\u3064\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%96%B9%E6%B3%95\"><\/span>\u65b9\u6cd5<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u672c\u8ad6\u6587\u3067\u306f\u3001\u4e0b\u8a18\u306e5\u3064\u306e\u30ac\u30f3\u7d30\u80de\u306e\u30da\u30a2\u306b\u3064\u3044\u30662\u30af\u30e9\u30b9\u5206\u985e\u3092\u884c\u3044\u307e\u3059<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>\u6de1\u660e\u814e\u7d30\u80de\u304c\u3093 (KIRC) vs. \u4e73\u982d\u72b6\u814e\u7d30\u80de\u304c\u3093 (KIRP)<\/li><li>\u80ba\u817a\u30ac\u30f3 (LUAD) vs. \u80ba\u6241\u5e73\u4e0a\u76ae\u30ac\u30f3 (LUSC)<\/li><li>\u6d78\u6f64\u6027\u4e73\u7ba1\u30ac\u30f3 (BRCA) vs. \u76ae\u75b9\u7d14\u6b63\u4e73\u7ba1\u30ac\u30f3 (normal)<\/li><li>\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\u967d\u6027\u4e73\u30ac\u30f3 (ERpos) vs. \u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\u967d\u6027\u4e73\u30ac\u30f3 (ERneg)<\/li><li>\u30eb\u30df\u30ca\u30eb\uff21\u4e73\u30ac\u30f3 (LumA) vs. \u30eb\u30df\u30ca\u30eb\uff22\u4e73\u30ac\u30f3 (LumB)<\/li><\/ul>\n\n\n\n<p>\u3053\u308c\u3089\u306b\u95a2\u3059\u308b\u30c7\u30fc\u30bf\u306fThe Cancer Genome Atlas (TCGA) Data\u304b\u3089\u53d6\u5f97\u3057\u307e\u3059\u3002\u30ac\u30f3\u3092\u8b58\u5225\u3059\u308b\u969b\u306b\u306f\u3001\u4ee5\u4e0b5\u7a2e\u985e\u306e\u7269\u8cea\u306e\u30c7\u30fc\u30bf\u3092\u53c2\u8003\u306b\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>messenger-RNA (mRNA)<\/li><li>micro-RNA (miRNA)<\/li><li>copy number variation (CNV)<\/li><li>single nucleotide polymorphism<\/li><li>DNA methylation<\/li><\/ul>\n\n\n\n<p>\u5b9f\u9a13\u306e\u6982\u7565\u56f3\u3092\u56f31\u306b\u793a\u3057\u307e\u3059\u30025\u3064\u306e\u7269\u8cea\u305d\u308c\u305e\u308c\u306b\u3064\u3044\u3066\u3001\u5404\u30c7\u30fc\u30bf\u306e\u7279\u5fb4\u30d9\u30af\u30c8\u30eb\u3092\u884c\u6210\u5206\u3068\u3057\u3066\u6301\u3064\u884c\u5217\u3092\u751f\u6210\u3057\u3001\u305d\u308c\u3089\u3092\u4e00\u3064\u306e\u884c\u5217\u306b\u7d50\u5408\u3059\u308b\u3053\u3067\u3001\u5b66\u7fd2\u30c7\u30fc\u30bf\u3092\u7528\u610f\u3057\u307e\u3059\u3002\u5b66\u7fd2\u30c7\u30fc\u30bf\u306e\u3046\u3061\u300180%\u3092\u8a13\u7df4\u30c7\u30fc\u30bf\u3068\u3057\u300120%\u3092\u30c6\u30b9\u30c8\u30c7\u30fc\u30bf\u3068\u3057\u307e\u3059\u3002\u8a13\u7df4\u30c7\u30fc\u30bf\u306b\u306f\u6a19\u6e96\u5316\u3092\u884c\u3044\u307e\u3059\u3002\u3053\u306e\u884c\u5217\u306b\u5bfe\u3057\u3066\u4e3b\u6210\u5206\u5206\u6790\u3092\u7528\u3044\u300144\u500b\u306e\u7279\u5fb4\u91cf\u306b\u7d5e\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter\"><img decoding=\"async\" src=\"\/T-Wave\/wp-content\/uploads\/2022\/04\/19a1c7be2316dcab3582e6285c9afc01-scaled.jpg\" alt=\"\" class=\"wp-image-3366\"\/><figcaption>\u56f31\uff1a\u5b9f\u9a13\u306e\u6982\u7565\u56f3\uff08doi:&nbsp;<a href=\"https:\/\/dx.doi.org\/10.1016%2Fj.patter.2021.100246\" target=\"_blank\" rel=\"noreferrer noopener\">10.1016\/j.patter.2021.100246<\/a>\uff09<\/figcaption><\/figure><\/div>\n\n\n\n<p>\u30c6\u30b9\u30c8\u30c7\u30fc\u30bf\u306e\u5206\u985e\u306f\u8a13\u7df4\u30c7\u30fc\u30bf\u306b\u3088\u3063\u3066\u4e88\u3081\u8a13\u7df4\u3055\u308c\u305f\u5206\u985e\u5668\u306b\u3088\u3063\u3066\u884c\u308f\u308c\u307e\u3059\u3002\u672c\u8ad6\u6587\u3067\u306f10\u7a2e\u985e\u306e\u5206\u985e\u30e2\u30c7\u30eb\u3092\u4f5c\u6210\u3057\u307e\u3059\u3002\u5206\u985e\u30e2\u30c7\u30eb\u306f\u3001\u5f93\u6765\u578b\u306e\u6a5f\u68b0\u5b66\u7fd2\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u7528\u3044\u308b\u624b\u6cd5\u3068\u3001\u30a4\u30b8\u30f3\u30b0\u6a21\u578b\u3092\u7528\u3044\u305f\u624b\u6cd5\u306b\u5206\u3051\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><span style=\"text-decoration: underline;\"><strong>\u5f93\u6765\u578b\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0<\/strong><\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>\u30e9\u30c3\u30bd\u56de\u5e30 (LASSO)<\/li><li>\u30ea\u30c3\u30b8\u56de\u5e30 (Ridge)<\/li><li>\u30e9\u30f3\u30c0\u30e0\u30d5\u30a9\u30ec\u30b9\u30c8 (Random Forest)<\/li><li>\u5358\u7d14\u30d9\u30a4\u30ba (NB)<\/li><li>\u30b5\u30dd\u30fc\u30c8\u30d9\u30af\u30c8\u30eb\u30de\u30b7\u30f3 (SVM)<\/li><\/ul>\n\n\n\n<p><span style=\"text-decoration: underline;\"><strong>\u30a4\u30b8\u30f3\u30b0\u578b\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0<\/strong><\/span><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>D-Wave\uff08D-Wave Systems \u306e D-Wave 2X\u3068\u3044\u3046\u91cf\u5b50\u30a2\u30cb\u30fc\u30ea\u30f3\u30b0\u30de\u30b7\u30f3\u3092\u4f7f\u7528\u3059\u308b\uff09<\/li><li>\u30b7\u30df\u30e5\u30ec\u30fc\u30c6\u30c3\u30c9\u30a2\u30cb\u30fc\u30ea\u30f3\u30b0 (SA)<\/li><li>Field<\/li><li>Random<\/li><li>\u5236\u9650\u30dc\u30eb\u30c4\u30de\u30f3\u30de\u30b7\u30f3(RBM)<\/li><\/ul>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306b\u3064\u3044\u3066\u3092\u7c21\u6f54\u306b\u8aac\u660e\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305a\u3001LASSO\u306f\u3001\u6b21\u5f0f\u3067\u5b9a\u7fa9\u3055\u308c\u308b\u3001L1\u6b63\u5247\u5316\u7dda\u5f62\u56de\u5e30\u30e2\u30c7\u30eb\u3067\u3059\u3002<\/p>\n\n\n\n<p>$$<br>\\hat{\\beta}({\\lambda})=\\min_{\\beta}[-log[L(y;{\\beta})]+{\\lambda}|| {\\beta} ||_1] \\tag{1}<br>$$<\/p>\n\n\n\n<p>\u307e\u305f\u3001Ridge\u306f\u3001\u6b21\u5f0f\u3067\u5b9a\u7fa9\u3055\u308c\u308b\u3001L2\u6b63\u5247\u5316\u7dda\u5f62\u56de\u5e30\u30e2\u30c7\u30eb\u3067\u3059\u3002<\/p>\n\n\n\n<p>$$<br>\\hat{\\beta}({\\lambda})=\\min_{\\beta}[-log[L(y;{\\beta})]+{\\lambda}|| {\\beta} ||_2^2] \\tag{2}<br>$$<\/p>\n\n\n\n<p>\u305f\u3060\u3057\u3001<\/p>\n\n\n\n<p>$$<br>L= \\frac{1}{N} \\sum_{i=1}^{N}(y_i &#8211; {\\beta}_0 &#8211; x_i {\\cdot}{\\beta})^2 \\tag{3}<br>$$<\/p>\n\n\n\n<p>\u3067\u3042\u308a\u3001$\\lambda \\gt 0$ \u306f\u30e2\u30c7\u30eb\u306e\u8907\u96d1\u3055\u3092\u5236\u5fa1\u3059\u308b\u6b63\u5247\u5316\u30d1\u30e9\u30e1\u30fc\u30bf\u3001$\\beta$ \u306f\u56de\u5e30\u4fc2\u6570\u3001$\\beta_0$ \u306f\u30d0\u30a4\u30a2\u30b9\u3001$y$ \u306f\u30af\u30e9\u30b9\u30e9\u30d9\u30eb\u3001$x_i$ \u306f $i$ \u756a\u76ee\u306e\u8a13\u7df4\u30b5\u30f3\u30d7\u30eb\u3092\u6307\u3057\u307e\u3059\u3002\u5b66\u7fd2\u306e\u76ee\u7684\u306f\u3001\u5404\u5f0f\u306e\u91cf\u3092\u6700\u5c0f\u306b\u3059\u308b\u3088\u3046\u306a\u56de\u5e30\u4fc2\u6570 $\\hat{\\beta}$ \u3092\u6c42\u3081\u308b\u3053\u3068\u3067\u3059\u3002\u4e88\u6e2c\u30e9\u30d9\u30eb\u306f\u3001$\\hat{y} = \\beta_0+x_i {\\cdot}{\\beta}$ \u3067\u4e0e\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u4eca\u56de\u6271\u3046SVM\u306f\u3001\u5f0f(4)\u3067\u5b9a\u7fa9\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>$$<br>{\\max_a}{L_D}(a) = \\sum_{i=1}^{N}a_i&nbsp; &#8211; \\frac{1}{2}&nbsp; \\sum_{i,j=1}^{N}a_ia_jy_iy_jK(x_i,x_j) \\tag{4}<br>$$<\/p>\n\n\n\n<p>\u305f\u3060\u3057\u3001$L_D$\u306f\u554f\u984c\u306e\u30e9\u30b0\u30e9\u30f3\u30b8\u30e5\u306e\u53cc\u5bfe\u6027\u3001$a_i$\u306f\u30e9\u30b0\u30e9\u30f3\u30b8\u30e5\u306e\u672a\u5b9a\u4e57\u6570\u3001$y_i, y_j$\u306fi\u756a\u76ee\u306e\u30e9\u30d9\u30eb\u3068\u8a13\u7df4\u30b5\u30f3\u30d7\u30eb\u3001$K(x_i, x_j)$\u306f\u30ab\u30fc\u30cd\u30eb\u95a2\u6570\u3092\u8868\u3057\u307e\u3059\u3002$ \\sum_{i=1}^{N}{a_i}{y_i} = 0 $\u3068${a_i}\\geq{C}\\geq{0} $\u306e\u5236\u7d04\u306e\u5143\u3001\u6700\u5927\u5024\u3092\u635c\u7d22\u3057\u307e\u3059\u3002\u3053\u3053\u3067\u3001$C$\u306f\u3001\u975e\u7dda\u5f62\u5206\u985e\u5668\u306b\u304a\u3051\u308b\u8aa4\u5206\u985e\u306e\u5ea6\u5408\u3044\u3092\u5236\u5fa1\u3059\u308b\u30cf\u30a4\u30d1\u30fc\u30d1\u30e9\u30e1\u30fc\u30bf\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u30a4\u30b8\u30f3\u30b0\u578b\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306b\u304a\u3044\u3066\u306f\u3001\u30cf\u30df\u30eb\u30c8\u30cb\u30a2\u30f3\u304c\u6b21\u5f0f\u3067\u8868\u3055\u308c\u308b\u3088\u3046\u306a\u30a4\u30b8\u30f3\u30b0\u6a21\u578b\u3068\u3057\u3066\u5b66\u7fd2\u306e\u76ee\u7684\u95a2\u6570\u3092\u5b9a\u7fa9\u3057\u3001\u6700\u9069\u5316\u3092\u884c\u3046\u3053\u3068\u3067\u5206\u985e\u5668\u306e\u8a13\u7df4\u3092\u884c\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>$$<br>H_p = \\sum_{i}h_i{\\sigma}_i + \\sum_{i,j}J_{i.j}{\\sigma}_i{\\sigma}_j \\tag{5}<br>$$<\/p>\n\n\n\n<p>\u305f\u3060\u3057\u3001${\\sigma}_i \\in {-1, 1} $\u306f\u30b9\u30d4\u30f3\u5909\u6570\u3092\u8868\u3057\u307e\u3059\u3002$h_i$\u5c40\u6240\u78c1\u5834\u3001$J_{i,j}$\u306f\u30b9\u30d4\u30f3\u9593\u306e\u76f8\u4e92\u4f5c\u7528\u3092\u8868\u3059\u5b9a\u6570\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u91cf\u5b50\u30a2\u30cb\u30fc\u30ea\u30f3\u30b0\u306f\u6a2a\u78c1\u5834\u306b\u3088\u308b\u91cf\u5b50\u3086\u3089\u304e\u3092\u7528\u3044\u3066\u30a8\u30cd\u30eb\u30ae\u30fc\u304c\u6700\u5c0f\u3068\u306a\u308b\u89e3\u3092\u63a2\u7d22\u3057\u307e\u3059\u3002\u4eca\u56de\u306fD-Wave Systems\u304c\u516c\u958b\u3057\u3066\u3044\u308b\u3001D-Wave 2X\u3068\u3044\u3046\u5b9f\u6a5f\u306e\u91cf\u5b50\u30a2\u30cb\u30fc\u30ea\u30f3\u30b0\u30de\u30b7\u30f3\u3092\u4f7f\u7528\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4eca\u56de\u8ad6\u6587\u3067\u306f\u660e\u8a18\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u304c\u3001\u4eca\u56de\u306e2\u30af\u30e9\u30b9\u5206\u985e\u306e\u5834\u5408\u306b\u5f53\u3066\u306f\u3081\u3066\u3053\u308c\u3092\u8003\u3048\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u4e00\u3064\u76ee\u306e2\u30af\u30e9\u30b9\u5206\u985e\u3067\u3042\u308bKIRC vs. KIRP\u3067\u306f\u3001$\\sigma=1$\u3067\u30b5\u30f3\u30d7\u30eb\u304cKIRC\u3067\u3042\u3063\u305f\u5834\u5408\u3001$\\sigma=-1$\u3067\u30b5\u30f3\u30d7\u30eb\u304cKIRP\u3067\u3042\u3063\u305f\u5834\u5408\u3092\u6307\u3059\u3068\u3057\u307e\u3059\u3002\u4e0a\u3067\u8ff0\u3079\u305f\u3001\u5404\u884c\u304c\u30b5\u30f3\u30d7\u30eb\u3001\u5404\u5217\u304c\u907a\u4f1d\u5b50\u306b\u5f53\u305f\u308b\u884c\u5217\u306e\u5206\u5e03\u3068\u4e01\u5ea6\u91cd\u306a\u308b\u3088\u3046\u306b\u3001\u30d1\u30e9\u30e1\u30fc\u30bf$h_i$\u3068$J_{i,j}$\u3092\u8fd4\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001SA\u306f\u3001\u540c\u69d8\u306b\u5f0f(5)\u306e\u30a4\u30b8\u30f3\u30b0\u554f\u984c\u3092\u53d7\u3051\u53d6\u308a\u3001\u4e8c\u5024\u3092\u8fd4\u3059\u8a08\u7b97\u5668\u3067\u3059\u3002\u672c\u6765\u3001\u30a4\u30b8\u30f3\u30b0\u30a8\u30cd\u30eb\u30ae\u30fc\u304c\u6700\u5c0f\u306b\u306a\u308b\u3088\u3046\u89e3\u3092\u63a2\u7d22\u3057\u307e\u3059\u304c\u3001\u30b7\u30df\u30e5\u30ec\u30fc\u30c6\u30c3\u30c9\u30a2\u30cb\u30fc\u30ea\u30f3\u30b0\u3067\u306f\u3001\u6700\u9069\u89e3\u3092\u63a2\u3059\u969b\u306b\u3001\u57fa\u672c\u7684\u306b\u306f\u5024\u304c\u5c0f\u3055\u304f\u306a\u308b\u65b9\u5411\u306b\u63a2\u7d22\u3057\u307e\u3059\u304c\u3001\u305d\u306e\u5185\u78ba\u7387$p$\u3067\u3001\u9006\u306b\u5024\u304c\u5927\u304d\u304f\u306a\u308b\u65b9\u5411\u3078\u9032\u307f\u307e\u3059\u3002\u78ba\u7387$p$\u306f\u3001\u6700\u521d\u306f\u5927\u304d\u304f\u3001\u6642\u9593\u304c\u7d4c\u3064\u306b\u3064\u308c\u3066\u5c0f\u3055\u304f\u306a\u308b\u3082\u306e\u3068\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>Field\u3067\u306f\u3001\u540c\u69d8\u306b\u5f0f(5)\u3067\u4eca\u5ea6\u306f$J_{i,j}$\u306f\u7121\u8996\u3057\u3001\u8a13\u7df4\u30c7\u30fc\u30bf\u3092\u57fa\u306b\u3092\u6c42\u3081\u307e\u3059\u3002\u6700\u5f8c\u306b${\\sigma_i}^{field} = -h_i$\u3068\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>Random\u3067\u306f\u3001\u5f0f(5)\u304b\u3089\u30e9\u30f3\u30c0\u30e0\u306b\u89e3\u3092\u751f\u6210\u3057\u307e\u3059\u3002\u5404${\\sigma}_i$\u306b\u30e9\u30f3\u30c0\u30e0\u306b[0, 1)\u306e\u7bc4\u56f2\u306e\u5024\u3092\u4e0e\u3048\u30010.5\u4ee5\u4e0b\u306e\u3082\u306e\u306f-1\u306b\u30010.5\u4ee5\u4e0a\u306e\u3082\u306e\u306f+1\u3068\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>RBM\u306f\u3001\u53ef\u8996\u5c64\u3068\u96a0\u308c\u5c64\u3068\u3044\u3046\u4e8c\u3064\u306e\u5c64\u304b\u3089\u6210\u308b\u78ba\u7387\u30e2\u30c7\u30eb\u3067\u3059\u3002\u5165\u529b\u5206\u5e03\u3092\u53ef\u8996\u5c64\u306b\u5165\u529b\u3057\u3066\u5b66\u7fd2\u3092\u884c\u3044\u3001\u5b66\u7fd2\u30d1\u30e9\u30e1\u30fc\u30bf\u304c\u8fd4\u3055\u308c\u307e\u3059\u3002\u53ef\u8996\u5c64\u306e\u8981\u7d20\u3092$v_i$\u3001\u96a0\u308c\u5c64\u306e\u8981\u7d20\u3092$h_j$\u3068\u3057\u307e\u3059\u3002\u5404\u8981\u7d20\u306e\u30d0\u30a4\u30a2\u30b9\u3092\u305d\u308c\u305e\u308c$b_i, c_j$\u3068\u3057\u307e\u3059\u3002\u96a0\u308c\u5c64\u3068\u53ef\u8996\u5c64\u306e\u9593\u306e\u7d50\u5408\u306e\u91cd\u307f\u3092$W_{i,j}$\u3068\u3059\u308b\u3068\u3001\u4ee5\u4e0b\u30a8\u30cd\u30eb\u30ae\u30fc\u95a2\u6570<\/p>\n\n\n\n<p>$$<br>E(v,h) = -\\sum_i{b_i}{v_i} &#8211; \\sum_j{c_j}{h_j} -\\sum_i\\sum_j{v_i}{W_{i,j}}{h_j} \\tag{6}<br>$$<\/p>\n\n\n\n<p>\u3092\u7528\u3044\u3066\u3001RBM\u306f\u5f0f(7)\u306e\u3088\u3046\u306b\u5b9a\u7fa9\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>$$<br>P(v,h) = \\frac{\\exp\\{-E(v,h)\\}}{Z(W)} \\tag{7}<br>$$<\/p>\n\n\n\n<p>\u305f\u3060\u3057\u3001Z\u306f\u6b63\u5247\u5316\u4fc2\u6570\u3067\u3059\u3002\u5f0f(7)\u306e\u78ba\u7387\u5206\u5e03\u304c\u5165\u529b\u30c7\u30fc\u30bf\u306e\u5206\u5e03\u306b\u5408\u3046\u3088\u3046\u306b\u3001\u30d1\u30e9\u30e1\u30fc\u30bf\u3092\u8abf\u6574\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%B5%90%E6%9E%9C1%EF%BD%9C%E3%82%AC%E3%83%B3%E7%A8%AE%E9%A1%9E%E5%88%A5%E3%81%AE%E5%88%86%E9%A1%9E%E6%80%A7%E8%83%BD\"><\/span>\u7d50\u679c1\uff5c\u30ac\u30f3\u7a2e\u985e\u5225\u306e\u5206\u985e\u6027\u80fd<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u5206\u985e\u5668\u3092\u7528\u3044\u3066\u524d\u7ae0\u3067\u8ff0\u3079\u305f5\u3064\u306e2\u30af\u30e9\u30b9\u5206\u985e\u3092\u884c\u3044\u3001\u305d\u308c\u305e\u308c\u306e\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306e\u7cbe\u5ea6\u3092\u6bd4\u8f03\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u8a13\u7df4\u30c7\u30fc\u30bf\u3068\u30c6\u30b9\u30c8\u30c7\u30fc\u30bf\u306b\u3064\u3044\u3066\u300c\u6b63\u89e3\u7387\u300d\u3001\u300c\u4e0d\u5747\u8861\u30c7\u30fc\u30bf\u3092\u8003\u616e\u3057\u305f\u6b63\u89e3\u7387\u300d\u3001\u300cAUC\u300d\u3001\u300cF\u5024\u300d\u306e4\u3064\u306e\u6307\u6a19\u3067\u5206\u985e\u5668\u306e\u7cbe\u5ea6\u3092\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002\u5404\u6307\u6a19\u306b\u95a2\u3059\u308b\u8a73\u7d30\u306b\u3064\u3044\u3066\u306f\u88dc\u8db3\u306e\u7ae0\u3092\u53c2\u7167\u304f\u3060\u3055\u3044\u3002\u8a13\u7df4\u30c7\u30fc\u30bf\u3068\u30c6\u30b9\u30c8\u30c7\u30fc\u30bf100\u500b\u306e\u4e0d\u5747\u8861\u30c7\u30fc\u30bf\u3092\u8003\u616e\u3057\u305f\u6b63\u89e3\u7387\u3092\u5143\u306b\u3001\u9806\u4f4d\u3092\u4ed8\u3051\u307e\u3057\u305f\u3002\u9806\u4f4d\u306e\u9ad8\u3044\u9806\u756a\u306b\u6a2a\u8ef8\u306b\u4e26\u3079\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5b9f\u9a13\u7d50\u679c\u3092\u56f32\u306b\u793a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-image wp-image-3363\"><figure class=\"aligncenter\"><img decoding=\"async\" src=\"\/T-Wave\/wp-content\/uploads\/2022\/04\/e06fd9aec8d3c680610494ba8b5c6646.jpg\" alt=\"\" class=\"wp-image-3363\"\/><figcaption>\u56f32\uff1a\u5b9f\u9a131\u306e\u7d50\u679c\u3002\u4e94\u3064\u306e2\u30af\u30e9\u30b9\u5206\u985e\u306b\u5bfe\u3057\u3001\u6a2a\u8ef8\u304c\u5206\u985e\u5668\u3001\u7e26\u8ef8\u304c\u5404\u5206\u985e\u5668\u306e\u6027\u80fd\u306e\u9ad8\u3055\u3092\u793a\u3057\u307e\u3059\u3002\u8272\u3067\u5206\u3051\u3089\u308c\u3066\u3044\u308b\u30b0\u30e9\u30d5\u306e\u7dda\u5206\u306f\u3001\u6027\u80fd\u3092\u8a55\u4fa1\u3059\u308b\u5404\u6307\u6a19\u3092\u793a\u3057\u307e\u3059\u3002\u5404\u30b0\u30e9\u30d5\u306b\u304a\u3044\u3066\u3001\u4e0d\u5747\u8861\u30c7\u30fc\u30bf\u3092\u8003\u616e\u3057\u305f\u6b63\u89e3\u7387\u306e\u9ad8\u3044\u5206\u985e\u5668\u304c\u30b0\u30e9\u30d5\u306e\u5de6\u5074\u306b\u3042\u308a\u307e\u3059\u3002\uff08<a href=\"https:\/\/doi.org\/10.1016\/j.patter.2021.100246\">10.1016\/j.patter.2021.100246<\/a>\uff09<\/figcaption><\/figure><\/div>\n\n\n\n<p>ERpos vs. ERneg\u306e2\u30af\u30e9\u30b9\u5206\u985e\u3067\u306f\u3001SVM\u306e\u6027\u80fd\u304c\u6700\u3082\u826f\u304f\u3001Field\u304c\u6700\u3082\u60aa\u3044\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3059\u3002\u30a4\u30b8\u30f3\u30b0\u578b\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306b\u95a2\u3057\u3066\u306f\u3001\u6027\u80fd\u306e\u9ad8\u3044\u9806\u304b\u3089\u3001RBM2\u4f4d\u3001Random6\u4f4d\u3001SA7\u4f4d\u3001D-Wave8\u4f4d\u3001Field10\u4f4d\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u540c\u3058\u3088\u3046\u306b\u3001\u4ed6\u306e2\u30af\u30e9\u30b9\u5206\u985e\u3067\u3082\u3001\u30a4\u30b8\u30f3\u30b0\u578b\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306e\u9806\u4f4d\u306f\u3070\u3089\u3064\u3044\u3066\u304a\u308a\u3001\u6a5f\u68b0\u5b66\u7fd2\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306e\u65b9\u304c\u3084\u3084\u6027\u80fd\u304c\u9ad8\u3044\u50be\u5411\u306b\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%B5%90%E6%9E%9C2%EF%BD%9C%E5%AD%A6%E7%BF%92%E3%83%87%E3%83%BC%E3%82%BF%E6%95%B0%E3%81%AE%E4%BE%9D%E5%AD%98%E6%80%A7\"><\/span><strong>\u7d50\u679c2\uff5c\u5b66\u7fd2\u30c7\u30fc\u30bf\u6570\u306e\u4f9d\u5b58\u6027<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u3055\u3066\u3001\u5206\u985e\u5668\u306e\u6027\u80fd\u304c\u3001\u8a13\u7df4\u30c7\u30fc\u30bf\u306e\u30b5\u30a4\u30ba\u306b\u4f9d\u5b58\u3059\u308b\u3053\u3068\u304c\u5148\u884c\u7814\u7a76\u3067\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u3053\u3067\u3001\u8a13\u7df4\u30c7\u30fc\u30bf\u306e\u30b5\u30a4\u30ba\u3092\u5f90\u3005\u306b\u6e1b\u5c11\u3055\u305b\u3001\u8a13\u7df4\u30c7\u30fc\u30bf\u30b5\u30a4\u30ba\u306b\u5bfe\u3059\u308b\u5404\u5206\u985e\u5668\u306e\u6027\u80fd\u3092\u8a55\u4fa1\u3057\u307e\u3059\u3002\u672c\u5b9f\u9a13\u306fLumA vs. LumB\u306e2\u30af\u30e9\u30b9\u5206\u985e\u3067\u691c\u8a3c\u3057\u307e\u3059\u3002\u5143\u3005\u8a13\u7df4\u30c7\u30fc\u30bf\u304c250\u30b5\u30f3\u30d7\u30eb\u3042\u308b\u3068\u3053\u308d\u3092\u3001\u6700\u5c0f50\u30b5\u30f3\u30d7\u30eb\uff08\u5143\u306e\u30c7\u30fc\u30bf\u30b5\u30a4\u30ba\u306e20%\uff09\u306b\u307e\u3067\u6e1b\u5c11\u3055\u305b\u3066\u3044\u304d\u307e\u3059\u3002\u5b9f\u9a13\u306e\u7d50\u679c\u3092\u56f33\u306b\u793a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-image wp-image-3360\"><figure class=\"aligncenter\"><img decoding=\"async\" src=\"\/T-Wave\/wp-content\/uploads\/2022\/04\/82ff0dac7b1e238b4260d60258b263a8.jpg\" alt=\"\" class=\"wp-image-3360\"\/><figcaption>\u56f33\uff1a\u5b66\u7fd2\u30c7\u30fc\u30bf\u6570\u306e\u4f9d\u5b58\u6027\u3002\u6a2a\u8ef8\u304c\u8a13\u7df4\u30c7\u30fc\u30bf\u306b\u7528\u3044\u305f\u5143\u306e\u8a13\u7df4\u30c7\u30fc\u30bf\u306e\u5272\u5408\u3001\u7e26\u8ef8\u304c\u5404\u5206\u985e\u5668\u306e\u4e0d\u5747\u8861\u30c7\u30fc\u30bf\u3092\u8003\u616e\u3057\u305f\u6b63\u89e3\u7387\u3092\u793a\u3057\u307e\u3059\u3002\uff08<a href=\"https:\/\/doi.org\/10.1016\/j.patter.2021.100246\">10.1016\/j.patter.2021.100246<\/a>\uff09<\/figcaption><\/figure><\/div>\n\n\n\n<p>\u4eca\u56de\u306f\u3001\u4e0d\u5747\u8861\u30c7\u30fc\u30bf\u3092\u8003\u616e\u3057\u305f\u6b63\u89e3\u7387\u306b\u7d5e\u3063\u3066\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u8a13\u7df4\u30c7\u30fc\u30bf\u30b5\u30a4\u30ba\u306e\u6e1b\u5c11\u306b\u4f34\u3044\u3001SVM\u3001Ridge\u3001LASSO\u306e\u6b63\u89e3\u7387\u306f\u5f90\u3005\u306b\u4e0b\u304c\u3063\u3066\u3044\u307e\u3059\u3002RF\u3084NB\u306e\u6b63\u89e3\u7387\u306f\u4e00\u8cab\u3057\u3066\u4ed6\u306e\u5206\u985e\u5668\u3088\u308a\u4f4e\u3044\u307e\u307e\u3067\u3059\u3002\u305d\u308c\u306b\u5bfe\u3057\u3001\u6b8b\u308a\u306eD-Wave\u3001Field\u3001Random\u3001RBM\u3001SA\u306f\u6982\u306d\u6b63\u89e3\u7387\u304c\u4fdd\u305f\u308c\u3066\u3044\u307e\u3059\u3002\u5177\u4f53\u7684\u306a\u6570\u5024\u3092\u793a\u3059\u3068\u3001\u30a4\u30b8\u30f3\u30b0\u30e2\u30c7\u30eb\u306e\u6027\u80fd\u306f\u3001\u8a13\u7df4\u30c7\u30fc\u30bf\u30b5\u30a4\u30ba95%\u30670.76\u300120%\u30670.73\u3068\u307b\u307c\u4e0b\u304c\u3089\u306a\u304f\u3001LASSO\u3067\u306f0.75\u304b\u30890.60\u306b\u4e0b\u304c\u308a\u307e\u3057\u305f\u3002\u307e\u305f\u30015\u3064\u306e\u6a5f\u68b0\u5b66\u7fd2\u5206\u985e\u5668\u306f\u5168\u3066\u904e\u5b66\u7fd2\u3092\u8d77\u3053\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u672c\u7d50\u679c\u306b\u3088\u308a\u30a4\u30b8\u30f3\u30b0\u578b\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306f\u5c11\u306a\u3044\u30c7\u30fc\u30bf\u304b\u3089\u91cd\u8981\u306a\u7279\u5831\u91cf\u3092\u628a\u63e1\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u3066\u3044\u305f\u3068\u8a00\u3048\u307e\u3059\u3002\u5f0f(5)\u3067\u8ff0\u3079\u305f\u901a\u308a\u3001\u30a4\u30b8\u30f3\u30b0\u578b\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306f\u3001\u30a4\u30b8\u30f3\u30b0\u30cf\u30df\u30eb\u30c8\u30cb\u30a2\u30f3\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u304c\u6700\u5c0f\u3068\u306a\u308b$\\sigma_i$\u3092\u63a2\u7d22\u3059\u308b\u3088\u3046\u52d5\u4f5c\u3057\u307e\u3059\u304c\u3001\u5fc5\u305a\u3057\u3082\u6700\u5c0f\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u3068\u306a\u308b\u5024\u3092\u8fd4\u3059\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u6a5f\u68b0\u5b66\u7fd2\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u307b\u3069\u5206\u985e\u306e\u7cbe\u5ea6\u3092\u91cd\u8996\u3057\u306a\u3044\u305f\u3081\u3001\u904e\u5b66\u7fd2\u3092\u8d77\u3053\u3055\u305a\u306b\u5c11\u91cf\u306e\u8a13\u7df4\u30c7\u30fc\u30bf\u3067\u3082\u6027\u80fd\u3092\u7dad\u6301\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u305f\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%B5%90%E8%AB%96\"><\/span>\u7d50\u8ad6<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u4ee5\u4e0a\u306e\u3088\u3046\u306b\u3001\u6a5f\u68b0\u5b66\u7fd2\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u3068\u30a4\u30b8\u30f3\u30b0\u578b\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u3092\u7528\u3044\u3066\u3001\u30ac\u30f3\u306e2\u30af\u30e9\u30b9\u5206\u985e\u3092\u884c\u3044\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u30c7\u30fc\u30bf\u30b5\u30a4\u30ba\u306e\u5927\u304d\u3044\u30c7\u30fc\u30bf\u306b\u5bfe\u3057\u3066\u306f\u3001\u30a4\u30b8\u30f3\u30b0\u578b\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u5206\u985e\u5668\u306f\u6a5f\u68b0\u5b66\u7fd2\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306e\u5206\u985e\u5668\u3068\u540c\u7b49\u3001\u3042\u308b\u3044\u306f\u3084\u3084\u52a3\u308b\u6027\u80fd\u3092\u898b\u305b\u307e\u3057\u305f\u3002\u6b21\u306b\u3001\u8a13\u7df4\u30c7\u30fc\u30bf\u30b5\u30a4\u30ba\u3092\u6e1b\u5c11\u3055\u305b\u305f\u3068\u3053\u308d\u3001\u6a5f\u68b0\u5b66\u7fd2\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306f\u6027\u80fd\u304c\u6e1b\u5c11\u3057\u305f\u306e\u306b\u5bfe\u3057\u3001\u30a4\u30b8\u30f3\u30b0\u578b\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306f\u307b\u307c\u4e00\u5b9a\u306e\u6b63\u89e3\u7387\u3092\u4fdd\u3061\u307e\u3057\u305f\u3002\u3053\u306e\u7d50\u679c\u304b\u3089\u3001\u30a4\u30b8\u30f3\u30b0\u578b\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306f\u3001\u30c7\u30fc\u30bf\u91cf\u306e\u9650\u3089\u308c\u3066\u3044\u308b\u30c7\u30fc\u30bf\u306e\u5206\u6790\u306b\u6709\u7528\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E3%81%82%E3%81%A8%E3%81%8C%E3%81%8D\"><\/span>\u3042\u3068\u304c\u304d<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u6a5f\u68b0\u5b66\u7fd2\u3084\u91cf\u5b50\u30a2\u30cb\u30fc\u30ea\u30f3\u30b0\u306e\u624b\u6cd5\u3092\u5b9f\u8df5\u7684\u306a\u5185\u5bb9\u3067\u5e45\u5e83\u304f\u52c9\u5f37\u3059\u308b\u3053\u3068\u304c\u51fa\u6765\u307e\u3057\u305f\u3002\u305d\u308c\u305e\u308c\u306e\u5206\u985e\u5668\u306e\u9577\u6240\u3084\u77ed\u6240\u3092\u3088\u308a\u8a73\u7d30\u306b\u77e5\u308a\u305f\u3044\u3068\u601d\u3044\u307e\u3057\u305f\u3002\u305d\u308c\u305e\u308c\u306e\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306b\u3088\u308b\u5177\u4f53\u7684\u306a\u5206\u985e\u65b9\u6cd5\u306e\u8aac\u660e\u304c\u3042\u308c\u3070\u3088\u308a\u5206\u304b\u308a\u3084\u3059\u304b\u3063\u305f\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%9C%AC%E8%A8%98%E4%BA%8B%E3%81%AE%E6%8B%85%E5%BD%93%E8%80%85\"><\/span>\u672c\u8a18\u4e8b\u306e\u62c5\u5f53\u8005<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u7530\u5c3b\u88d5\u7f8e\u5b50 (\u7de8\u96c6\u8005\uff1a\u4e38\u5c71\u5c1a\u8cb4\u3001\u7fbd\u5834\u5ec9\u4e00\u90ce)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E8%A3%9C%E8%B6%B3%EF%BD%9C%E8%A9%95%E4%BE%A1%E6%8C%87%E6%A8%99%E3%81%AB%E3%81%A4%E3%81%84%E3%81%A6\"><\/span>\u88dc\u8db3\uff5c\u8a55\u4fa1\u6307\u6a19\u306b\u3064\u3044\u3066<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u5206\u985e\u5668\u306e\u7cbe\u5ea6\u306f\u3001\u300c\u6b63\u89e3\u7387\u300d\u3001\u300c\u4e0d\u5747\u8861\u30c7\u30fc\u30bf\u3092\u8003\u616e\u3057\u305f\u6b63\u89e3\u7387\u300d\u3001\u300cAUC\u300d\u3001\u300cF\u5024\u300d\u306e4\u3064\u306e\u6307\u6a19\u3067\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002\u305d\u308c\u305e\u308c\u306e\u8aac\u660e\u3092\u6b21\u306b\u793a\u3057\u307e\u3059\u3002<a href=\"https:\/\/www.codexa.net\/ml-evaluation-cls\/\">\u6a5f\u68b0\u5b66\u7fd2\u306e\u8a55\u4fa1\u6307\u6a19 \u5206\u985e\u7de8<\/a>\u3092\u53c2\u8003\u306b\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u6b21\u306e\u3088\u3046\u306a\u6df7\u5408\u884c\u5217\u3092\u8003\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-image wp-block-image-table\"><figure class=\"aligncenter\"><figcaption>\u88681: \u6df7\u5408\u884c\u5217\u30022\u5024\u5206\u985e\u554f\u984c\u306b\u304a\u3044\u3066\u3001\u4e88\u6e2c\u3068\u5b9f\u969b\u306e\u5206\u985e\u3092\u884c\u5217\u5f62\u5f0f\u306b\u307e\u3068\u3081\u305f\u3082\u306e\u3002\u300c\u4e88\u6e2c\u300d\u3068\u306f\u3001\u4e88\u6e2c\u3057\u305f\u7d50\u679c\u306e\u3053\u3068\u3067\u3001\u300c\u5b9f\u969b\u300d\u3068\u306f\u3001\u5b9f\u969b\u306b\u305d\u306e\u30b5\u30f3\u30d7\u30eb\u304c\u9670\u6027\u304b\u967d\u6027\u3060\u3063\u305f\u304b\u3092\u6307\u3057\u307e\u3059\u3002<\/figcaption><img decoding=\"async\" src=\"\/T-Wave\/wp-content\/uploads\/2023\/04\/dc9c063efd0998d7ada3e352d2364387-300x213.png\" alt=\"\" class=\"wp-image-3406\"><\/figure><\/div>\n\n\n\n<p>\u8868\uff11\u3067\u306f\u3001\u305d\u308c\u305e\u308c\u306e\u30de\u30b9\u76ee\u306f\u6b21\u306e\u3053\u3068\u3092\u793a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>\u771f\u9670\u6027(TN)\uff1a\u691c\u67fb\u3067\u9670\u6027\u3068\u3055\u308c\u3001\u5b9f\u969b\u306b\u9670\u6027\u3067\u3042\u308b\u5834\u5408<\/li><li>\u507d\u9670\u6027(FN)\uff1a\u691c\u67fb\u3067\u9670\u6027\u3068\u3055\u308c\u305f\u3082\u306e\u306e\u3001\u5b9f\u969b\u306b\u306f\u967d\u6027\u3067\u3042\u308b\u5834\u5408<\/li><li>\u507d\u967d\u6027(FP)\uff1a\u691c\u67fb\u3067\u967d\u6027\u3068\u3055\u308c\u305f\u3082\u306e\u306e\u3001\u5b9f\u969b\u306b\u306f\u9670\u6027\u3067\u3042\u308b\u5834\u5408<\/li><li>\u771f\u967d\u6027(TP)\uff1a\u691c\u67fb\u3067\u967d\u6027\u3068\u3055\u308c\u3001\u5b9f\u969b\u306b\u967d\u6027\u3067\u3042\u308b\u5834\u5408<\/li><\/ul>\n\n\n\n<p>\u306a\u304a\u3001\u4eca\u56de\u306f\u30ac\u30f3\u306e\u5206\u985e\u3067\u3042\u308b\u305f\u3081\u3001\u4f8b\u3048\u3070KIRC vs. KIRP\u306e2\u30af\u30e9\u30b9\u5206\u985e\u3067\u306f\u3001\u6df7\u5408\u884c\u5217\u306f\u8868\uff12\u306e\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-image wp-block-image-table\"><figure class=\"aligncenter\"><figcaption>\u88682: KIRC vs. KIRP\u306e2\u30af\u30e9\u30b9\u5206\u985e\u306e\u5834\u5408\u306e\u6df7\u5408\u884c\u5217<\/figcaption><img decoding=\"async\" src=\"\/T-Wave\/wp-content\/uploads\/2023\/04\/KIRC-vs.-KIRP-300x216.png\" alt=\"\" class=\"wp-image-3405\"><\/figure><\/div>\n\n\n\n<p>\u6b63\u89e3\u7387\u306f\u3001\u5f0f(8)\u3067\u5b9a\u7fa9\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>$$<br>\\textrm{Accuracy} = \\frac{TP+TN}{TP+FP+TN+FN} \\tag{8}<br>$$<\/p>\n\n\n\n<p>\u5168\u4e88\u6e2c\u306e\u5185\u3001\u6b63\u89e3\u3057\u305f\u4e88\u6e2c\u306e\u5272\u5408\u3092\u6307\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u4eca\u56de\u6271\u3046AUC\u306f\u3001ROC\u66f2\u7dda\u4e0b\u306e\u9762\u7a4d\u306e\u4e8b\u3092\u6307\u3057\u307e\u3059\u3002ROC\u66f2\u7dda\u306f\u3001\u6a2a\u8ef8\u306b\u507d\u967d\u6027\u7387\u3001\u7e26\u8ef8\u306b\u518d\u73fe\u7387\u3092\u53d6\u3063\u305f\u66f2\u7dda\u3067\u3059\u3002\u305d\u306e\u66f2\u7dda\u306e\u4e0b\u306e\u9762\u7a4d\u306f0\u304b\u30891\u306e\u5024\u3092\u53d6\u308a\u3001\u305d\u306e\u5024\u304c\u5927\u304d\u3044\u307b\u3069\u826f\u3044\u4e88\u6e2c\u304c\u51fa\u6765\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>F\u5024\u306b\u3064\u3044\u3066\u3001\u307e\u305a\u3001\u9069\u5408\u7387(Precision)\u3068\u518d\u73fe\u7387(Recall)\u3092\u5b9a\u7fa9\u3059\u308b\u3068\u3001<\/p>\n\n\n\n<p>$$<br>\\textrm{Precision} = \\frac{TP}{TP+FP} \\tag{9}<br>$$<\/p>\n\n\n\n<p>$$<br>\\textrm{Recall} = \\frac{TP}{TP+FN} \\tag{10}<br>$$<\/p>\n\n\n\n<p>\u3067\u3059\u3002\u9069\u5408\u7387\u306f\u3001\u967d\u6027\u3068\u4e88\u6e2c\u3057\u305f\u3082\u306e\u306e\u3046\u3061\u3001\u5b9f\u969b\u306b\u967d\u6027\u3067\u3042\u308b\u3082\u306e\u306e\u5272\u5408\u3092\u8868\u3057\u307e\u3059\u3002\u518d\u73fe\u7387\u306f\u3001\u5b9f\u969b\u306b\u967d\u6027\u3067\u3042\u308b\u3082\u306e\u306e\u3046\u3061\u3001\u6b63\u3057\u304f\u967d\u6027\u3068\u4e88\u6e2c\u3055\u308c\u305f\u3082\u306e\u306e\u5272\u5408\u3092\u8868\u3057\u307e\u3059\u3002\u3053\u308c\u3067\u3001F\u5024\u306f\u3001<\/p>\n\n\n\n<p>$$<br>F-measure = \\frac{2\\times{Precision}\\times{Recall}}{Precision+Recall} \\tag{11}<br>$$<\/p>\n\n\n\n<p>\u3068\u5b9a\u7fa9\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n","protected":false},"excerpt":{"rendered":"<p>\u672c\u8ad6\u6587\u3067\u306f\u91cf\u5b50\u30a2\u30cb\u30fc\u30ea\u30f3\u30b0\u3092\u7528\u3044\u3066\u30ac\u30f3\u30c7\u30fc\u30bf\u306e\u5206\u985e\u3092\u884c\u3044\u3001\u65e2\u5b58\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u3068\u306e\u6bd4\u8f03\u8a55\u4fa1\u3092\u884c\u3044\u307e\u3059\u3002\u91cf\u5b50\u30a2\u30cb\u30fc\u30ea\u30f3\u30b0\u306f\u3001\u91cf\u5b50\u52b9\u679c\u3092\u7528\u3044\u3066\u30a4\u30b8\u30f3\u30b0\u6a21\u578b\u306e\u57fa\u5e95\u72b6\u614b\u3092\u63a2\u7d22\u3057\u307e\u3059\u3002\u3053\u306e\u30a4\u30b8\u30f3\u30b0\u6a21\u578b\u306e\u57fa\u5e95\u72b6\u614b\u3092\u53e4\u5178\u7684\u306a\u8a08\u7b97\u306b\u3088\u3063\u3066\u63a2\u7d22\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306a\u30b7\u30df\u30e5\u30ec\u30fc\u30c6\u30c3\u30c9\u30a2\u30cb\u30fc\u30ea\u30f3\u30b0\u306e\u6027\u80fd\u3082\u8a55\u4fa1\u3057\u307e\u3059\u3002\u305d\u306e\u7d50\u679c\u3001\u30a4\u30b8\u30f3\u30b0\u6a21\u578b\u3092\u7528\u3044\u305f\u6a5f\u68b0\u5b66\u7fd2\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306f\u3001\u5b66\u7fd2\u30c7\u30fc\u30bf\u304c\u5c11\u306a\u3044\u5834\u5408\u306b\u512a\u308c\u305f\u5206\u985e\u6027\u80fd\u3092\u6301\u3064\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n","protected":false},"author":14,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[10,11,12,35,41,56,71,73,83,88,104,122],"class_list":["post-3353","post","type-post","status-publish","format-standard","hentry","category-review","tag-d-wave","tag-d-wave-2000q","tag-d-wave-2x","tag-rbm","tag-svm","tag-56","tag-71","tag-73","tag-83","tag-88","tag-104","tag-122"],"yoast_head":"<!-- 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